Event took place on February 21, 2010 at the Scottrade Center in St. Louis, Missouri. It was the first Elimination Chamber event. Six matches were aired on the broadcast and one dark match occurred prior to the live broadcast.
The concept of the event was that the two main event matches, one each for the World Heavyweight Championship and the WWE Championship, would occur in an Elimination Chamber. Each match featured six competitors: the defending champion and five challengers. Sheamus defended the WWE Championship against Triple H, Ted DiBiase, Randy Orton, John Cena, and Kofi Kingston in the Raw Elimination Chamber. In the SmackDown Elimination Chamber match, The Undertaker defended the World Heavyweight Championship against Chris Jericho, John Morrison, Rey Mysterio, CM Punk and R-Truth. On the undercard, Drew McIntyre defended the WWE Intercontinental Championship against Kane, The Miz defended the WWE United States Championship against Montel Vontavious Porter, and Maryse and Gail Kim competed against Team Lay-Cool (Layla and Michelle McCool) in an interbrand Divas tag team match.